%P 325-350 %T Radical innovation and network evolution %I Association pour le d?veloppement de la recherch? en ?conomie et en statistique %V 87-88 %K Pharmaceutical industry; Biotechnology industry; R&D; Technological change; Alliances; Networks; %A Sandra Phlippen %A Massimo Riccaboni %D 2007 %L eprints1060 %X This paper examines how a radical technological innovation affects alliance formation of firms and subsequent network structures. We use longitudinal data of interfirm R&D collaborations in the biopharmaceutical industry in which a new technological regime is established. Our findings suggest that it requires radical technological change for firms to leave their embedded path of existing alliances and form new alliances with new partners. While new partners are mostly found through the firms? existing network, we provide some insight into distant link formation with unknown partners, which contributes to our understanding of how ?small-worlds? might emerge %J Annales d'Economie et de Statistique / Annals of Economics and Statistics