eprintid: 1094 rev_number: 9 eprint_status: archive userid: 6 dir: disk0/00/00/10/94 datestamp: 2012-02-01 11:33:12 lastmod: 2018-03-08 17:05:45 status_changed: 2012-02-01 11:33:12 type: article metadata_visibility: show creators_name: Ahnert, Sebastian E. creators_name: Garlaschelli, Diego creators_name: Fink, Thomas M.A. creators_name: Caldarelli, Guido creators_id: creators_id: diego.garlaschelli@imtlucca.it creators_id: creators_id: guido.caldarelli@imtlucca.it title: Applying weighted network measures to microarray distance matrices ispublished: pub subjects: QA subjects: QC subjects: QH301 divisions: EIC full_text_status: none keywords: PACS: 87.16.Yc Regulatory genetic and chemical networks; 02.10.Yn Matrix theory; 87.10.-e General theory and mathematical aspects; 87.80.-y Biophysical techniques (research methods) abstract: In recent work we presented a new approach to the analysis of weighted networks, by providing a straightforward generalization of any network measure defined on unweighted networks. This approach is based on the translation of a weighted network into an ensemble of edges, and is particularly suited to the analysis of fully connected weighted networks. Here we apply our method to several such networks including distance matrices, and show that the clustering coefficient, constructed by using the ensemble approach, provides meaningful insights into the systems studied. In the particular case of two datasets from microarray experiments the clustering coefficient identifies a number of biologically significant genes, outperforming existing identification approaches. date: 2008-06 publication: Journal of Physics A: Mathematical and Theoretical volume: 41 number: 22 publisher: Institute of Physics pagerange: 224011 id_number: 10.1088/1751-8113/41/22/224011 refereed: TRUE issn: 1751-8113 official_url: http://dx.doi.org/10.1088/1751-8113/41/22/224011 citation: Ahnert, Sebastian E. and Garlaschelli, Diego and Fink, Thomas M.A. and Caldarelli, Guido Applying weighted network measures to microarray distance matrices. Journal of Physics A: Mathematical and Theoretical, 41 (22). p. 224011. ISSN 1751-8113 (2008)