TY - JOUR Y1 - 2000/12// UR - http://dx.doi.org/10.1103/PhysRevE.62.8449 PB - American Physical Society KW - PACS: 87.14.Ee SN - 1539-3755 JF - Physical Review E ID - eprints1156 A1 - De Los Rios, Paolo A1 - Caldarelli, Guido TI - Putting proteins back into water N2 - We introduce a simplified protein model where the solvent (water) degrees of freedom appear explicitly (although in an extremely simplified fashion). Using this model we are able to recover the thermodynamic phenomenology of proteins over a wide range of temperatures. In particular we describe both the warm and the cold protein denaturation within a single framework, while addressing important issues about the structure of model proteins. IS - 6 VL - 62 EP - 8452 AV - none SP - 8449 ER -