TY  - CHAP
AV  - public
TI  - Controlled drug administration by a fractional PID
ID  - eprints2327
UR  - http://www.ifac-papersonline.net/Detailed/67921.html
N1  - 19th IFAC World Congress, August 24-29, 2014, Cape Town, South Africa
KW  - Biomedical control; Biomedical systems; Pharmacokinetics and drug delivery; Control of physiological and clinical variables; Physiological model; Fractional control 
N2  - Amiodarone is an antiarrhythmic drug that exhibits highly complex and non-exponential dynamics whose controlled administration has important implications for its clinical use especially for long-term therapies. Its pharmacokinetics has been accurately modelled using a fractional-order compartmental model. In this paper we design a fractional-order PID controller and we evaluate its dynamical characteristics in terms of the stability margins of the closed loop and the ability of the controlled system to attenuate various sources of noise and uncertainty. 
PB  - IFAC
EP  - 8426
SN  - 978-3-902823-62-5
SP  - 8421
Y1  - 2014/08//
T2  - Proceedings of the 19th IFAC World Congress
A1  - Sopasakis, Pantelis
A1  - Sarimveis, Haralambos
ER  -