eprintid: 2327
rev_number: 12
eprint_status: archive
userid: 6
dir: disk0/00/00/23/27
datestamp: 2014-10-21 13:19:35
lastmod: 2014-10-22 08:17:50
status_changed: 2014-10-21 13:19:35
type: book_section
metadata_visibility: show
creators_name: Sopasakis, Pantelis
creators_name: Sarimveis, Haralambos
creators_id: pantelis.sopasakis@imtlucca.it
creators_id: 
title: Controlled drug administration by a fractional PID
ispublished: pub
subjects: QA75
subjects: RM
divisions: CSA
full_text_status: public
pres_type: paper
keywords: Biomedical control; Biomedical systems; Pharmacokinetics and drug delivery; Control of physiological and clinical variables; Physiological model; Fractional control 
note: 19th IFAC World Congress, August 24-29, 2014, Cape Town, South Africa
abstract: Amiodarone is an antiarrhythmic drug that exhibits highly complex and non-exponential dynamics whose controlled administration has important implications for its clinical use especially for long-term therapies. Its pharmacokinetics has been accurately modelled using a fractional-order compartmental model. In this paper we design a fractional-order PID controller and we evaluate its dynamical characteristics in terms of the stability margins of the closed loop and the ability of the controlled system to attenuate various sources of noise and uncertainty. 
date: 2014-08
date_type: published
publisher: IFAC
pagerange: 8421-8426
event_title: 19th IFAC World Congress
event_location: Cape Town, South Africa
event_dates: August 24-29, 2014
event_type: conference
id_number: 10.3182/20140824-6-ZA-1003.00740
refereed: TRUE
isbn: 978-3-902823-62-5
book_title: Proceedings of the 19th IFAC World Congress
official_url: http://www.ifac-papersonline.net/Detailed/67921.html
citation:   Sopasakis, Pantelis and Sarimveis, Haralambos  Controlled drug administration by a fractional PID.   In:  Proceedings of the 19th IFAC World Congress.   IFAC, pp. 8421-8426.  ISBN 978-3-902823-62-5      (2014)  
document_url: http://eprints.imtlucca.it/2327/1/PreprintSopasakisIFAC14.pdf