relation: http://eprints.imtlucca.it/2421/ title: Quantitative comparison of reconstruction methods for intra-voxel fiber recovery from diffusion MRI creator: Daducci, Alessandro creator: Canales-Rodriguez, Erick Jorge creator: Descoteaux, Maxime creator: Garyfallidis, Eleftherios creator: Gur, Yaniv creator: Lin, Ying-Chia creator: Mani, Merry creator: Merlet, Sylvain creator: Paquette, Michael creator: Ramirez-Manzanares, Alonso creator: Reisert, Marco creator: Reis Rodrigues, Paulo creator: Sepehrband, Farshid creator: Caruyer, Emmanuel creator: Choupan, Jeiran creator: Deriche, Rachid creator: Jacob, Matthew creator: Menegaz, Gloria creator: Prckovska, Vesna creator: Rivera, Mariano creator: Wiaux, Yves creator: Thiran, Jean-Philippe subject: QA75 Electronic computers. Computer science subject: RC Internal medicine description: Validation is arguably the bottleneck in the diffusion magnetic resonance imaging (MRI) community. This paper evaluates and compares 20 algorithms for recovering the local intra-voxel fiber structure from diffusion MRI data and is based on the results of the “HARDI reconstruction challenge” organized in the context of the “ISBI 2012” conference. Evaluated methods encompass a mixture of classical techniques well known in the literature such as diffusion tensor, Q-Ball and diffusion spectrum imaging, algorithms inspired by the recent theory of compressed sensing and also brand new approaches proposed for the first time at this contest. To quantitatively compare the methods under controlled conditions, two datasets with known ground-truth were synthetically generated and two main criteria were used to evaluate the quality of the reconstructions in every voxel: correct assessment of the number of fiber populations and angular accuracy in their orientation. This comparative study investigates the behavior of every algorithm with varying experimental conditions and highlights strengths and weaknesses of each approach. This information can be useful not only for enhancing current algorithms and develop the next generation of reconstruction methods, but also to assist physicians in the choice of the most adequate technique for their studies. publisher: IEEE date: 2014-02 type: Article type: PeerReviewed identifier: Daducci, Alessandro and Canales-Rodriguez, Erick Jorge and Descoteaux, Maxime and Garyfallidis, Eleftherios and Gur, Yaniv and Lin, Ying-Chia and Mani, Merry and Merlet, Sylvain and Paquette, Michael and Ramirez-Manzanares, Alonso and Reisert, Marco and Reis Rodrigues, Paulo and Sepehrband, Farshid and Caruyer, Emmanuel and Choupan, Jeiran and Deriche, Rachid and Jacob, Matthew and Menegaz, Gloria and Prckovska, Vesna and Rivera, Mariano and Wiaux, Yves and Thiran, Jean-Philippe Quantitative comparison of reconstruction methods for intra-voxel fiber recovery from diffusion MRI. IEEE Transactions on Medical Imaging, 33 (2). pp. 384-399. ISSN 0278-0062 (2014) relation: http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6630106&isnumber=6729093 relation: 10.1109/TMI.2013.2285500