TY - CHAP A1 - Mukhopadhyay, Anirban A1 - Oksuz, Ilkay A1 - Bevilacqua, Marco A1 - Tsaftaris, Sotirios A. PB - Springer SN - 978-3-319-20309-6 SP - 189 M1 - 9126 N2 - Cardiac Phase-resolved Blood Oxygen-Level-Dependent (CP-BOLD) MR is capable of diagnosing an ongoing ischemia by detecting changes in myocardial intensity patterns at rest without any contrast and stress agents. Visualizing and detecting these changes require significant post-processing, including myocardial segmentation for isolating the myocardium. But, changes in myocardial intensity pattern and myocardial shape due to the heart?s motion challenge automated standard CINE MR myocardial segmentation techniques resulting in a significant drop of segmentation accuracy. We hypothesize that the main reason behind this phenomenon is the lack of discernible features. In this paper, a multi scale discriminative dictionary learning approach is proposed for supervised learning and sparse representation of the myocardium, to improve the myocardial feature selection. The technique is validated on a challenging dataset of CP-BOLD MR and standard CINE MR acquired in baseline and ischemic condition across 10 canine subjects. The proposed method significantly outperforms standard cardiac segmentation techniques, including segmentation via registration, level sets and supervised methods for myocardial segmentation. TI - Data-driven feature learning for myocardial segmentation of CP-BOLD MRI AV - none KW - Dictionary learning; CP-BOLD MR; CINE MR; Segmentation Y1 - 2015/06/21/ UR - http://link.springer.com/chapter/10.1007%2F978-3-319-20309-6_22 ID - eprints2746 EP - 197 T2 - Functional imaging and modeling of the heart ER -