@article{eprints2934, volume = {236}, month = {February}, number = {2}, pages = {138--144}, title = {Functional inhibition of the human middle temporal cortex affects non-visual motion perception: a repetitive transcranial magnetic stimulation study during tactile speed discrimination}, year = {2011}, journal = {Experimental Biology and Medicine}, publisher = {SAGE}, author = {Emiliano Ricciardi and Demis Basso and Lorenzo Sani and Daniela Bonino and Tomaso Vecchi and Pietro Pietrini and Carlo Miniussi}, url = {http://eprints.imtlucca.it/2934/}, abstract = {The visual motion-responsive middle temporal complex (hMT+) is activated during tactile and aural motion discrimination in both sighted and congenitally blind individuals, suggesting a supramodal organization of this area. Specifically, non-visual motion processing has been found to activate the more anterior portion of the hMT+. In the present study, repetitive transcranial magnetic stimulation (rTMS) was used to determine whether this more anterior portion of hMT+ truly plays a functional role in tactile motion processing. Sixteen blindfolded, young, healthy volunteers were asked to detect changes in the rotation velocity of a random Braille-like dot pattern by using the index or middle finger of their right hand. rTMS was applied for 600 ms (10 Hz, 110\% motor threshold), 200 ms after the stimulus onset with a figure-of-eight coil over either the anterior portion of hMT+ or a midline parieto-occipital site (as a control). Accuracy and reaction times were significantly impaired only when TMS was applied on hMT+, but not on the control area. These results indicate that the recruitment of hMT+ is necessary for tactile motion processing, and thus corroborate the hypothesis of a ?supramodal? functional organization for this sensory motion processing area.} }