relation: http://eprints.imtlucca.it/3091/
title: Deficiency and supplementation of {PUFA} in the diet have similar effects on the age-associated changes in rat-plasma cholesterol levels
creator: Straniero, Sara
creator: Cavallini, Gabriella
creator: Donati, Alessio
creator: Metelli, Maria Rita
creator: Tamburini, Ilaria
creator: Pietrini, Pietro
creator: Bergamini, Ettore
subject: QH301 Biology
subject: QP Physiology
description: Levels of plasma cholesterol, particularly {LDL} cholesterol, increase with increasing age in humans and rodents. Feeding a fish oil-rich diet may exert hypocholesterolemic effects. The aim of this work was to examine the effects of a life-long administration of a PUFA-enriched diet and of a PUFA-deficient diet in male Sprague–Dawley rats on the age-associated increases in plasma cholesterol and triglycerides. Diet had small effects on body-weight, and had dramatic effects on liver phospholipids-fatty acids. Surprisingly, both diets counteracted the age-associated changes in plasma cholesterol and triglycerides similarly and benefits were already visible in adult rats.
publisher: Elsevier
date: 2008
type: Article
type: PeerReviewed
identifier:   Straniero, Sara and Cavallini, Gabriella and Donati, Alessio and Metelli, Maria Rita and Tamburini, Ilaria and Pietrini, Pietro and Bergamini, Ettore  Deficiency and supplementation of {PUFA} in the diet have similar effects on the age-associated changes in rat-plasma cholesterol levels.  Mechanisms of Ageing and Development, 129 (12).  759 - 762.  ISSN 0047-6374      (2008)  
relation: http://www.sciencedirect.com/science/article/pii/S0047637408001802
relation: 10.1016/j.mad.2008.09.009