TY - CONF N2 - A supervised learning paradigm is investigated, in which the data are represented by labeled regions of the input space. This learning model is motivated by real-world applications, such as problems of medical diagnosis and image categorization. The associated optimization framework entails the minimization of a functional obtained by introducing a loss function that involves the labeled regions. A regularization term expressed via differential operators, modeling smoothness properties of the desired input/output relationship, is included. It is shown that the optimization problem associated to supervised learning from regions has a unique solution, represented as a linear combination of kernel functions determined by the differential operators together with the regions themselves. The case of regions given by multi-dimensional intervals (i.e., ?boxes?) is investigated as an interesting instance of learning from regions, which models prior knowledge expressed by logical propositions. The proposed approach covers as a particular case the classical learning context, which corresponds to the situation where regions degenerate to single points. Applications and numerical examples are discussed. M2 - Como, Italy A1 - Gnecco, Giorgio A1 - Gori, Marco A1 - Melacci, Stefano A1 - Sanguineti, Marcello UR - http://www.cnr.it/istituti/Allegato_97592.pdf?LO=01000000d9c8b7a6090000000c000000cbb10000646f9c53000000000100000000000000000000000000000000000000000000000000000000000000000000000000000000000000&type=application/pdf Y1 - 2014/// KW - Supervised learning; Kernel machines; Infinite-dimensional optimization; Constrained variational calculus; Representer theorems. TI - Supervised Learning from Regions and Box Kernels AV - none T2 - 44th Conference of Italian Operational Research Society (AIRO 2014) ID - eprints3133 ER -