relation: http://eprints.imtlucca.it/3162/
title: The Effect of Visual Experience on the Development of Functional Architecture in hMT+
creator: Ricciardi, Emiliano
creator: Vanello, Nicola
creator: Sani, Lorenzo
creator: Gentili, Claudio
creator: Scilingo, Enzo Pasquale
creator: Landini, Luigi
creator: Guazzelli, Mario
creator: Bicchi, Antonio
creator: Haxby, James V.
creator: Pietrini, Pietro
subject: RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
description: We investigated whether the visual hMT+ cortex plays a role in supramodal representation of sensory flow, not mediated by visual mental imagery. We used functional magnetic resonance imaging to measure neural activity in sighted and congenitally blind individuals during passive perception of optic and tactile flows. Visual motion–responsive cortex, including hMT+, was identified in the lateral occipital and inferior temporal cortices of the sighted subjects by response to optic flow. Tactile flow perception in sighted subjects activated the more anterior part of these cortical regions but deactivated the more posterior part. By contrast, perception of tactile flow in blind subjects activated the full extent, including the more posterior part. These results demonstrate that activation of hMT+ and surrounding cortex by tactile flow is not mediated by visual mental imagery and that the functional organization of hMT+ can develop to subserve tactile flow perception in the absence of any visual experience. Moreover, visual experience leads to a segregation of the motion-responsive occipitotemporal cortex into an anterior subregion involved in the representation of both optic and tactile flows and a posterior subregion that processes optic flow only.
publisher: Oxford University press
date: 2007
type: Article
type: PeerReviewed
format: application/pdf
language: en
rights: cc_by_nc
identifier: http://eprints.imtlucca.it/3162/1/2933.full.pdf
identifier:   Ricciardi, Emiliano and Vanello, Nicola and Sani, Lorenzo and Gentili, Claudio and Scilingo, Enzo Pasquale and Landini, Luigi and Guazzelli, Mario and Bicchi, Antonio and Haxby, James V. and Pietrini, Pietro  The Effect of Visual Experience on the Development of Functional Architecture in hMT+.  Cerebral Cortex, 17 (12).  pp. 2933-2939.  ISSN 1047-3211      (2007)  
relation: http://cercor.oxfordjournals.org/content/17/12/2933.abstract
relation: 10.1093/cercor/bhm018