eprintid: 3162
rev_number: 8
eprint_status: archive
userid: 69
dir: disk0/00/00/31/62
datestamp: 2016-02-29 10:11:17
lastmod: 2016-09-13 10:09:03
status_changed: 2016-02-29 10:11:17
type: article
metadata_visibility: show
creators_name: Ricciardi, Emiliano
creators_name: Vanello, Nicola
creators_name: Sani, Lorenzo
creators_name: Gentili, Claudio
creators_name: Scilingo, Enzo Pasquale
creators_name: Landini, Luigi
creators_name: Guazzelli, Mario
creators_name: Bicchi, Antonio
creators_name: Haxby, James V.
creators_name: Pietrini, Pietro
creators_id: emiliano.ricciardi@imtlucca.it
creators_id: 
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creators_id: pietro.pietrini@imtlucca.it
title: The Effect of Visual Experience on the Development of Functional Architecture in hMT+
ispublished: pub
subjects: RC0321
divisions: CSA
full_text_status: public
keywords: Blind subjects; Functional magnetic resonance imaging (fMRI); hMT+; Optic flow; Supramodality; Tactile flow.
abstract: We investigated whether the visual hMT+ cortex plays a role in supramodal representation of sensory flow, not mediated by visual mental imagery. We used functional magnetic resonance imaging to measure neural activity in sighted and congenitally blind individuals during passive perception of optic and tactile flows. Visual motion–responsive cortex, including hMT+, was identified in the lateral occipital and inferior temporal cortices of the sighted subjects by response to optic flow. Tactile flow perception in sighted subjects activated the more anterior part of these cortical regions but deactivated the more posterior part. By contrast, perception of tactile flow in blind subjects activated the full extent, including the more posterior part. These results demonstrate that activation of hMT+ and surrounding cortex by tactile flow is not mediated by visual mental imagery and that the functional organization of hMT+ can develop to subserve tactile flow perception in the absence of any visual experience. Moreover, visual experience leads to a segregation of the motion-responsive occipitotemporal cortex into an anterior subregion involved in the representation of both optic and tactile flows and a posterior subregion that processes optic flow only.
date: 2007
date_type: published
publication: Cerebral Cortex
volume: 17
number: 12
publisher: Oxford University press
pagerange: 2933-2939
id_number: 10.1093/cercor/bhm018
refereed: TRUE
issn: 1047-3211
official_url: http://cercor.oxfordjournals.org/content/17/12/2933.abstract
citation:   Ricciardi, Emiliano and Vanello, Nicola and Sani, Lorenzo and Gentili, Claudio and Scilingo, Enzo Pasquale and Landini, Luigi and Guazzelli, Mario and Bicchi, Antonio and Haxby, James V. and Pietrini, Pietro  The Effect of Visual Experience on the Development of Functional Architecture in hMT+.  Cerebral Cortex, 17 (12).  pp. 2933-2939.  ISSN 1047-3211      (2007)  
document_url: http://eprints.imtlucca.it/3162/1/2933.full.pdf