@incollection{eprints3257,
       booktitle = {Recent Researches in Modern Medicine},
           title = {Controlled Release of the Anti-cancer Drug Paclitaxel from Bioresorbable Poly(ester-ether-ester) Microspheres},
            year = {2011},
       publisher = {WSEAS},
          author = {Giulio D. Guerra and Mariacristina Gagliardi and Niccoletta Barbani and Caterina Cristallini},
           pages = {210--217},
        abstract = {The release of the anti-cancer drug paclitaxel (PTX) from microspheres of the bioresorbable poly({\ensuremath{\epsilon}}-caprolactoneoxyethylene-{\ensuremath{\epsilon}}-caprolactone)tri-block copolymer was studied. The microspheres, both loaded and not with PTX, were prepared by emulsion-evaporation technique, then characterized by SEM, AFM, total reflection and spotlight FT-IR spectroscopy, and DSC. The quantities of PTX released were measured by HPLC. The results showed a slow and very regular release, which fits very well the Peppas equation, Mt/M? = k ? t, where Mt is the amount of solute released at the time t, M? is the amount of drug released at the plateau condition, k represents the Peppas kinetic constant and n the diffusion order.},
             url = {http://eprints.imtlucca.it/3257/}
}