@article{eprints3264, author = {Davide Silvestri and Caterina Cristallini and Mariacristina Gagliardi and Niccoletta Barbani and M. D'Acunto and G. Ciardelli and Paolo Giusti}, journal = {Journal of Biomaterials Applications}, publisher = {Sage}, number = {4}, pages = {353--383}, volume = {24}, year = {2009}, title = {Acrylic Copolymers as Candidates for Drug-Eluting Coating of Vascular Stents}, abstract = {The aim of the present work is the synthesis and characterization of polymer materials showing good adhesion, drug loading, and delivery properties, for potential cardiovascular application. In particular, poly(methylmethacrylate-co-acrylic acid) copolymers are prepared in different compositions by a radical polymerization and investigated as potential materials to coat metallic stents and to carry out a local drug release. Films obtained by dissolving the copolymer in an appropriate organic solvent (also loaded with an anti-restenosis drug, such as tacrolimus) are investigated: physicochemical properties, adhesiveness to metallic stent material, and kinetics of drug release in physiological environment are studied.}, url = {http://eprints.imtlucca.it/3264/} }