@article{eprints3323,
         journal = {Neuropsychobiology},
       publisher = {Karger},
          author = {Donatella Marazziti and Pietro Pietrini and Claudia Martini and Gino Giannaccini and Giulio Perugi and Gian Franco Placidi and Giovanni Battista Cassano and Antonio Lucacchini},
          volume = {18},
           pages = {74--76},
          number = {2},
           title = {A 3h-flunitrazepam binding inhibitor is present in psychiatric patients?sera},
            year = {1987},
             url = {http://eprints.imtlucca.it/3323/},
        abstract = {We investigated the possible existence of endogenous compounds acting on benzodiazepine central receptors in the serum of patients with panic attacks or depression. Our results show the presence of a substance which inhibits the 3H-fiunitrazepam binding specifically in the samples taken from the patients? groups, and which is not present in normal controls, in the range of concentrations used. This compound has a molecular weight below 1,000 daltons, is heat-stable, and resistant to proteolytic degradation. The demonstration of this inhibitor opens new perspectives in the study of the biochemistry of anxiety.}
}