eprintid: 3329
rev_number: 8
eprint_status: archive
userid: 69
dir: disk0/00/00/33/29
datestamp: 2016-03-23 13:49:49
lastmod: 2016-04-06 08:32:35
status_changed: 2016-03-23 13:49:49
type: article
metadata_visibility: show
creators_name: Pietrini, Pietro
creators_name: Azari, Nina P.
creators_name: Pettigrew, Karen D.
creators_name: Horwitz, Barry
creators_name: Kozachuk, W.
creators_name: Kumar, Anand
creators_name: Salerno, Judith A.
creators_name: Grady, Cheryl L.
creators_name: Haxby, James V.
creators_name: Aronin, N.
creators_name: Marshall, P.
creators_name: Schapiro, Mark B.
creators_id: pietro.pietrini@imtlucca.it
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title: Striatal Glucose Metabolism and Pattern of Cerebral Regional Interactions in Choreic Disorders
ispublished: pub
subjects: RC0321
divisions: CSA
full_text_status: none
abstract: With positron emission tomography (PET), cerebral glucose metabolism was studied in 5 patients with familial inverted chorea, a progressive choreiform disease with no dementia, and in age- and sex-matched control subjects. Computed tomography scans excluded cortical or striatal atrophy. PET scans showed no group differences in striatal glucose metabolism. However, when a discriminant analysis method was applied to the PET metabolic data, a discriminant function, reflecting functional interactions involving the striatum, successfully distinguished the patients from the control subjects. These results indicate striatal involvement in the pathophysiology of familial inverted chorea, and emphasize the importance of alternative methods of analyzing regional PET data.
date: 1993
date_type: published
publication: Journal of Neuroimaging
volume: 3
number: 3
publisher: Wiley
pagerange: 151-159
id_number: 10.1111/jon199333151
refereed: TRUE
issn: 1051-2284
official_url: http://dx.doi.org/10.1111/jon199333151
citation:   Pietrini, Pietro and Azari, Nina P. and Pettigrew, Karen D. and Horwitz, Barry and Kozachuk, W. and Kumar, Anand and Salerno, Judith A. and Grady, Cheryl L. and Haxby, James V. and Aronin, N. and Marshall, P. and Schapiro, Mark B.  Striatal Glucose Metabolism and Pattern of Cerebral Regional Interactions in Choreic Disorders.  Journal of Neuroimaging, 3 (3).  pp. 151-159.  ISSN 1051-2284      (1993)