@article{eprints3342, publisher = {Taylor and Francis}, pages = {1--20}, title = {Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data}, journal = {International Journal of Neuroscience}, year = {1995}, author = {Nina P. Azari and Karen D. Pettigrew and Pietro Pietrini and Declan G. Murphy and Barry Horwitz}, volume = {81}, number = {3-4}, abstract = {Sex differences in brain hemispheric structure and function have been reported, and sex-related differences in hemispheric interregional correlations were reported in a prior analysis of resting PET glucose metabolic (rCMRglc) data. To explore further the effect of sex on patterns of hemispheric brain functional interactions, we applied a multiple regression/discriminant analysis to resting rCMRglc PET data from young normal men and women to test two hypotheses: (1) women have stronger between-hemisphere functional interactions; (2) men have stronger within-hemisphere functional interactions. Two separate discriminant functions based on these hypotheses distinguished men and women: the first reflected rCMRglc interdependencies between hemispheres and correctly classified all women and 94\% of the men; the second reflected rCMRglc interdependencies within the left hemisphere and correctly classified 82\% of the women and 88\% of the men. Because the discriminant functions successfully distinguished men and women, these results provide support for both hypotheses.}, keywords = {Human; Sex; Positron emission tomography; Discriminant analysis; Cerebral metabolism; Brain.}, url = {http://eprints.imtlucca.it/3342/} }