relation: http://eprints.imtlucca.it/3342/ title: Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data creator: Azari, Nina P. creator: Pettigrew, Karen D. creator: Pietrini, Pietro creator: Murphy, Declan G. creator: Horwitz, Barry subject: RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry description: Sex differences in brain hemispheric structure and function have been reported, and sex-related differences in hemispheric interregional correlations were reported in a prior analysis of resting PET glucose metabolic (rCMRglc) data. To explore further the effect of sex on patterns of hemispheric brain functional interactions, we applied a multiple regression/discriminant analysis to resting rCMRglc PET data from young normal men and women to test two hypotheses: (1) women have stronger between-hemisphere functional interactions; (2) men have stronger within-hemisphere functional interactions. Two separate discriminant functions based on these hypotheses distinguished men and women: the first reflected rCMRglc interdependencies between hemispheres and correctly classified all women and 94% of the men; the second reflected rCMRglc interdependencies within the left hemisphere and correctly classified 82% of the women and 88% of the men. Because the discriminant functions successfully distinguished men and women, these results provide support for both hypotheses. publisher: Taylor and Francis date: 1995 type: Article type: PeerReviewed identifier: Azari, Nina P. and Pettigrew, Karen D. and Pietrini, Pietro and Murphy, Declan G. and Horwitz, Barry Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data. International Journal of Neuroscience, 81 (3-4). pp. 1-20. ISSN 0020-7454 (1995) relation: http://dx.doi.org/10.3109/00207459509015294 relation: 10.3109/00207459509015294