TY - JOUR ID - eprints3342 TI - Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data AV - none KW - Human; Sex; Positron emission tomography; Discriminant analysis; Cerebral metabolism; Brain. UR - http://dx.doi.org/10.3109/00207459509015294 IS - 3-4 VL - 81 PB - Taylor and Francis EP - 20 A1 - Azari, Nina P. A1 - Pettigrew, Karen D. A1 - Pietrini, Pietro A1 - Murphy, Declan G. A1 - Horwitz, Barry SP - 1 JF - International Journal of Neuroscience N2 - Sex differences in brain hemispheric structure and function have been reported, and sex-related differences in hemispheric interregional correlations were reported in a prior analysis of resting PET glucose metabolic (rCMRglc) data. To explore further the effect of sex on patterns of hemispheric brain functional interactions, we applied a multiple regression/discriminant analysis to resting rCMRglc PET data from young normal men and women to test two hypotheses: (1) women have stronger between-hemisphere functional interactions; (2) men have stronger within-hemisphere functional interactions. Two separate discriminant functions based on these hypotheses distinguished men and women: the first reflected rCMRglc interdependencies between hemispheres and correctly classified all women and 94% of the men; the second reflected rCMRglc interdependencies within the left hemisphere and correctly classified 82% of the women and 88% of the men. Because the discriminant functions successfully distinguished men and women, these results provide support for both hypotheses. SN - 0020-7454 Y1 - 1995/// ER -