eprintid: 3342 rev_number: 6 eprint_status: archive userid: 69 dir: disk0/00/00/33/42 datestamp: 2016-04-04 08:25:45 lastmod: 2016-04-04 11:54:45 status_changed: 2016-04-04 08:25:45 type: article metadata_visibility: show creators_name: Azari, Nina P. creators_name: Pettigrew, Karen D. creators_name: Pietrini, Pietro creators_name: Murphy, Declan G. creators_name: Horwitz, Barry creators_id: creators_id: creators_id: pietro.pietrini@imtlucca.it creators_id: creators_id: title: Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data ispublished: pub subjects: RC0321 divisions: CSA full_text_status: none keywords: Human; Sex; Positron emission tomography; Discriminant analysis; Cerebral metabolism; Brain. abstract: Sex differences in brain hemispheric structure and function have been reported, and sex-related differences in hemispheric interregional correlations were reported in a prior analysis of resting PET glucose metabolic (rCMRglc) data. To explore further the effect of sex on patterns of hemispheric brain functional interactions, we applied a multiple regression/discriminant analysis to resting rCMRglc PET data from young normal men and women to test two hypotheses: (1) women have stronger between-hemisphere functional interactions; (2) men have stronger within-hemisphere functional interactions. Two separate discriminant functions based on these hypotheses distinguished men and women: the first reflected rCMRglc interdependencies between hemispheres and correctly classified all women and 94% of the men; the second reflected rCMRglc interdependencies within the left hemisphere and correctly classified 82% of the women and 88% of the men. Because the discriminant functions successfully distinguished men and women, these results provide support for both hypotheses. date: 1995 date_type: published publication: International Journal of Neuroscience volume: 81 number: 3-4 publisher: Taylor and Francis pagerange: 1-20 id_number: 10.3109/00207459509015294 refereed: TRUE issn: 0020-7454 official_url: http://dx.doi.org/10.3109/00207459509015294 citation: Azari, Nina P. and Pettigrew, Karen D. and Pietrini, Pietro and Murphy, Declan G. and Horwitz, Barry Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data. International Journal of Neuroscience, 81 (3-4). pp. 1-20. ISSN 0020-7454 (1995)