@article{eprints3446, volume = {10}, number = {9}, title = {Individual differences in PET activation of object perception and attention systems predict face matching accuracy}, author = {Gene E. Alexander and Marc J. Mentis and J.D. Van Horn and Cheryl L. Grady and K.F. Berman and Maura L. Furey and Pietro Pietrini and Mark B. Schapiro and Stanley I. Rapoport and James R. Moeller}, year = {1999}, journal = {Neuroreport}, pages = {1965--1971}, publisher = {Wolters Kluver}, month = {June}, abstract = {WE sought to investigate how individual differences in the regional patterns of cerebral blood flow (rCBF) relate to task performance during the perceptual matching of faces. We analyzed rCBF data obtained by PET and H215O from nine young healthy, right-handed, adult males (mean age 29 {$\pm$} 3 years) using a statistical model of regional covariance, the Scaled Subprofile Model (SSM). SSM analysis performed on a voxel-basis for scan subtractions comparing face-matching and control tasks extracted two patterns whose subject expression in a multiple regression analysis was highly predictive of task accuracy (R2 = 0.87, p {\ensuremath{<}}0.002). The pattern reflecting this linear combination was principally characterized by higher rCBF in regions of bilateral occipital and occipitotemporal cortex, right orbitofrontal cortex, left thalamus, basal ganglia, midbrain, and cerebellum with relatively lower rCBF in anterior cingulate, regions in bilateral prefrontal and temporal cortex, right thalamus, and right inferior parietal cortex. The results indicate that individual subject differences in face matching performance are specifically associated with the functional interaction of cortical and subcortical brain regions previously implicated in aspects of object perception and visual attentional processing.}, url = {http://eprints.imtlucca.it/3446/} }