TY  - CHAP
UR  - http://doi.org/10.1109/IEMBS.2006.259272
A1  - Casarotto, Silvia
A1  - Bianchi, Anna M.
A1  - Cerutti, Sergio
A1  - Vanello, Nicola
A1  - Ricciardi, Emiliano
A1  - Gentili, Claudio
A1  - Sani, Lorenzo
A1  - Bonino, Daniela
A1  - Guazzelli, Mario
A1  - Pietrini, Pietro
A1  - Landini, Luigi
A1  - Chiarenza, Giuseppe A.
Y1  - 2006///
PB  - IEEE
T2  - Proceeding of the International Conference of the IEEE Engineering in Medicine and Biology Society
KW  - Magnetic resonance imaging
KW  -  Enterprise resource planning
KW  -  Independent component analysis
KW  -  Magnetic resonance
KW  -  Design for experiments
KW  -  Protocols
KW  -  Image resolution
KW  -  Tomography
KW  -  Current density
KW  -  Electromagnetic analysis
AV  - none
ID  - eprints3537
EP  - 987
SP  - 984
TI  - Combination of event-related potentials and functional magnetic resonance imaging during single-letter reading
N2  - This work proposes a mathematical approach for combining event-related potentials (ERPs) and functional magnetic resonance images (fMRI). Data were separately recorded during the same event-related experimental design, consisting of visually presented single letters and non-alphabetic symbols, that had to be either simply observed (passive condition) or read aloud (active condition). This protocol was useful for exploring the neural correlates of reading processes. Healthy adults participated in the experiment. Averaged ERPs were decomposed by independent component analysis; low resolution electromagnetic tomography (LORETA) was applied to estimate the current density distribution maps of each independent component. fMRI images time series were analyzed by multiple linear regression. ERP-fMRI correspondence was quantified by computing the Euclidean distance between LORETA local maxima and clusters of significantly activated fMRI voxels. During reading aloud of letters, that is clearly the task most similar to natural reading conditions, significant electrical and hemodynamic response was observed in the left medial frontal gyrus (BA 6) and left middle temporal gyrus (BA 22/39) just before articulation and in the bilateral middle superior temporal gyrus (BA 22/37) during and after verbal-motor production. These results indicate that the middle-superior temporal gyrus plays a crucial and multifunctional role in grapheme-phoneme matching
ER  -