%0 Book Section %A Sevetlidis, Vasileios %A Giuffrida, Mario Valerio %A Tsaftaris, Sotirios A. %B Simulation and Synthesis in Medical Imaging. First International Workshop, SASHIMI 2016, Held in Conjunction with MICCAI 2016, Athens, Greece, October 21, 2016, Proceedings %D 2016 %F eprints:3595 %I Springer International Publishing %N 9968 %P 127-137 %S Lecture Notes in Computer Science %T Whole Image Synthesis Using a Deep Encoder-Decoder Network %U http://eprints.imtlucca.it/3595/ %X The synthesis of medical images is an intensity transformation of a given modality in a way that represents an acquisition with a different modality (in the context of MRI this represents the synthesis of images originating from different MR sequences). Most methods follow a patch-based approach, which is computationally inefficient during synthesis and requires some sort of ‘fusion’ to synthesize a whole image from patch-level results. In this paper, we present a whole image synthesis approach that relies on deep neural networks. Our architecture resembles those of encoder-decoder networks, which aims to synthesize a source MRI modality to an other target MRI modality. The proposed method is computationally fast, it doesn’t require extensive amounts of memory, and produces comparable results to recent patch-based approaches.