TY  - JOUR
N2  - The brain is a paradigmatic example of a complex system: its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in terms of links (correlations) between nodes (grey matter regions) and to extract information out of the noise. Here we present the analysis of functional magnetic resonance imaging data from forty healthy humans at rest for the investigation of the basal scaffold of the functional brain network organization. We show how brain regions tend to coordinate by forming ahighly hierarchical chain-like structure of homogeneously clustered anatomical areas. A maximum spanning tree approach revealed the centrality of the occipital cortex and the peculiar aggregation of
cerebellar regions to form a closed core. We also report the hierarchy of network segregation and the level of clusters integration as a function of the connectivity strength between brain regions.
TI  - Organization and hierarchy of the human functional brain network lead to a chain-like core
ID  - eprints3732
SN  - 2045-2322
AV  - public
KW  - Complex networks; Network models
IS  - 1
PB  - Nature Publishing Group
VL  - 7
Y1  - 2017/07/07/
A1  - Mastrandrea, Rossana
A1  - Gabrielli, Andrea
A1  - Piras, Fabrizio
A1  - Spalletta, Gianfranco
A1  - Caldarelli, Guido
A1  - Gili, Tommaso
UR  - http://doi.org/10.1038/s41598-017-04716-3
JF  - Scientific Reports
ER  -