relation: http://eprints.imtlucca.it/3771/
title: Procoagulant control strategies for the human blood clotting process
creator: Laurino, Marco
creator: Menara, Tommaso
creator: Stella, Alessandro
creator: Betta, Monica
creator: Landi, Alberto
subject: QH301 Biology
subject: R Medicine (General)
description: This paper describes the comparison between two drug control strategies to hemophilia A. To emulate blood clotting and the pathological condition of hemophilia, a mathematical model composed by 14 ordinary differential equations is considered. We adopt a variable structure non-linear PID approach and a Model Predictive Control in order to control the dosage of procoagulant factor used in the treatment of hemophiliac patient. The two control actions are sampled for a practical application. Finally, we discuss and compare the results of the two control approaches, introducing a suited control index (eINR).
publisher: IEEE
date: 2015
type: Conference or Workshop Item
type: PeerReviewed
identifier:   Laurino, Marco and Menara, Tommaso and Stella, Alessandro and Betta, Monica and Landi, Alberto  Procoagulant control strategies for the human blood clotting process.  In: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), August 25-29, 2015, Milan, Italy pp. 4439-4442. ISSN 1558-4615. ISBN 978-1-4244-9271-8.      (2015)  
relation: http://doi.org/10.1109/EMBC.2015.7319380
relation: doi:10.1109/EMBC.2015.7319380