%0 Conference Paper
%A Laurino, Marco
%A Menara, Tommaso
%A Stella, Alessandro
%A Betta, Monica
%A Landi, Alberto
%B 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
%C Milan, Italy
%D 2015
%F eprints:3771
%I IEEE
%P 4439-4442
%T Procoagulant control strategies for the human blood clotting process
%U http://eprints.imtlucca.it/3771/
%X This paper describes the comparison between two drug control strategies to hemophilia A. To emulate blood clotting and the pathological condition of hemophilia, a mathematical model composed by 14 ordinary differential equations is considered. We adopt a variable structure non-linear PID approach and a Model Predictive Control in order to control the dosage of procoagulant factor used in the treatment of hemophiliac patient. The two control actions are sampled for a practical application. Finally, we discuss and compare the results of the two control approaches, introducing a suited control index (eINR).