TY  - CONF
EP  - 4442
T2  - 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
ID  - eprints3771
UR  - http://doi.org/10.1109/EMBC.2015.7319380
AV  - none
TI  - Procoagulant control strategies for the human blood clotting process
Y1  - 2015///
SP  - 4439
N2  - This paper describes the comparison between two drug control strategies to hemophilia A. To emulate blood clotting and the pathological condition of hemophilia, a mathematical model composed by 14 ordinary differential equations is considered. We adopt a variable structure non-linear PID approach and a Model Predictive Control in order to control the dosage of procoagulant factor used in the treatment of hemophiliac patient. The two control actions are sampled for a practical application. Finally, we discuss and compare the results of the two control approaches, introducing a suited control index (eINR).
A1  - Laurino, Marco
A1  - Menara, Tommaso
A1  - Stella, Alessandro
A1  - Betta, Monica
A1  - Landi, Alberto
M2  - Milan, Italy
SN  - 1558-4615
PB  - IEEE
ER  -