eprintid: 3771 rev_number: 6 eprint_status: archive userid: 69 dir: disk0/00/00/37/71 datestamp: 2017-09-04 13:44:51 lastmod: 2017-09-04 13:44:51 status_changed: 2017-09-04 13:44:51 type: conference_item metadata_visibility: show creators_name: Laurino, Marco creators_name: Menara, Tommaso creators_name: Stella, Alessandro creators_name: Betta, Monica creators_name: Landi, Alberto creators_id: creators_id: creators_id: creators_id: monica.betta@imtlucca.it creators_id: title: Procoagulant control strategies for the human blood clotting process ispublished: pub subjects: QH301 subjects: R1 divisions: CSA full_text_status: none pres_type: paper abstract: This paper describes the comparison between two drug control strategies to hemophilia A. To emulate blood clotting and the pathological condition of hemophilia, a mathematical model composed by 14 ordinary differential equations is considered. We adopt a variable structure non-linear PID approach and a Model Predictive Control in order to control the dosage of procoagulant factor used in the treatment of hemophiliac patient. The two control actions are sampled for a practical application. Finally, we discuss and compare the results of the two control approaches, introducing a suited control index (eINR). date: 2015 date_type: published publisher: IEEE pagerange: 4439-4442 event_title: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) event_location: Milan, Italy event_dates: August 25-29, 2015 event_type: conference id_number: doi:10.1109/EMBC.2015.7319380 refereed: TRUE isbn: 978-1-4244-9271-8 issn: 1558-4615 book_title: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) official_url: http://doi.org/10.1109/EMBC.2015.7319380 citation: Laurino, Marco and Menara, Tommaso and Stella, Alessandro and Betta, Monica and Landi, Alberto Procoagulant control strategies for the human blood clotting process. In: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), August 25-29, 2015, Milan, Italy pp. 4439-4442. ISSN 1558-4615. ISBN 978-1-4244-9271-8. (2015)