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primary topic: Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies

Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies
type: Manuscript
type: Article
abstract: Advanced therapies represent a paradigm shift. They offer potentially curative solutions to life-threatening diseases through a single administration. However, this paradigm shift poses unprecedented challenges to the current model of drug access and reimbursement developed for the management of conventional therapies, where reimbursement typically occurs at the time of therapy administration. In this paper, we identify the key determinants of the paradigm shift and propose a new reimbursement model for advanced therapies. The proposed model relies on managed entry agreements to address payer uncertainty and is based on conditional and deferred payments. The potential impact of such deferred payments on spending is estimated through horizon scanning. Finally, we propose the establishment of a dedicated fund to enable timely access to advanced therapies while ensuring the sustainability of the impact on pharmaceutical expenditure.
date: 2025
status: published
author list: authors
type: EPrint
type: MonographEPrint
is part of: repository
has document: Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies (PDF)
has version: Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies (PDF)
has published: Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies (PDF)
subject: HB Economic Theory
subject: HG Finance

Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies (PDF)
type: Document
license: http://creativecommons.org/licenses/by-nd/3.0/
has file: WP_1_2025_corretto.pdf
has part: WP_1_2025_corretto.pdf

IMT Institute for Advanced Studies Lucca
type: Organization

Federico Nutarelli
type: Person
given name: Federico
family name: Nutarelli

Massimo Riccaboni
type: Person
given name: Massimo
family name: Riccaboni

HTML Summary of #4088 Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies
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primary topic: Annuity and Conditional Payment Schemes for the Reimbursement of One-Shot Advanced Therapies

HB Economic Theory
type: Concept

HG Finance
type: Concept