TY - JOUR KW - Pharmaceutical industry; Biotechnology industry; R&D; Technological change; Alliances PB - Elsevier UR - http://www.sciencedirect.com/science/article/pii/S0048733300000949 SN - 0048-7333 JF - Research Policy ID - eprints629 Y1 - 2001/// EP - 508 AV - none SP - 485 TI - Technological change and network dynamics: Lessons from the pharmaceutical industry N2 - In this paper, we investigate how underlying relevant technological conditions induce distinguishable patterns of change in industry structure and evolution. A mapping is detected between the specific nature of problem decompositions and research techniques at the micro level of knowledge bases, and patterns of structural evolution at the macro level of the industry network. The graph-theoretic techniques we introduce map major technological discontinuities on changes observed at the level of dominant organization forms. They might have applications in other domains, whenever the identification of structural breaks and homological relationships between technological and industrial spaces are important issues. IS - 3 VL - 30 A1 - Pammolli, Fabio A1 - Orsenigo, Luigi A1 - Riccaboni, Massimo ER -