eprintid: 757 rev_number: 10 eprint_status: archive userid: 17 dir: disk0/00/00/07/57 datestamp: 2011-08-01 13:49:28 lastmod: 2011-08-08 08:40:22 status_changed: 2011-08-01 13:49:28 type: conference_item metadata_visibility: show item_issues_count: 0 creators_name: Kleijnen, Jack P.C. creators_name: Dellino, Gabriella creators_name: Meloni, Carlo creators_id: creators_id: gabriella.dellino@imtlucca.it creators_id: title: Robust simulation-optimization methodology ispublished: pub subjects: HA subjects: QA divisions: EIC full_text_status: none pres_type: paper abstract: This contribution summarizes a methodology for simulation optimization assuming some simulation inputs are uncertain. This methodology integrates Taguchi’s worldview (distinguishing between decision and environmental inputs), metamodeling (either Response Surface Methodology or Kriging), and mathematical programming. Instead of Taguchi’s statistical designs, this contribution uses Latin Hypercube Sampling for the environmental inputs. Mathematical programming is used to estimate the decision inputs that minimize the mean output, subject to a threshold for the standard deviation of the simulation output. Changing that threshold gives the estimated Pareto frontier. Confidence regions for the Pareto-optimal solution based on that frontier can be estimated through bootstrapping. This methodology is illustrated through Economic Order Quantity (EOQ) simulations. date: 2009 event_title: INFORMS Simulation Society Research Workshop event_type: workshop refereed: TRUE official_url: http://www.informs-sim.org/2009informs-simworkshop/paper50-54.pdf citation: Kleijnen, Jack P.C. and Dellino, Gabriella and Meloni, Carlo Robust simulation-optimization methodology. In: INFORMS Simulation Society Research Workshop (2009)