eprintid: 812 rev_number: 19 eprint_status: archive userid: 35 dir: disk0/00/00/08/12 datestamp: 2011-08-12 09:27:34 lastmod: 2013-03-05 15:47:33 status_changed: 2011-08-12 09:27:34 type: book_section metadata_visibility: show item_issues_count: 0 creators_name: Tsaftaris, Sotirios A. creators_name: Hatzimanikati, Vassily creators_name: Katsaggelos, Aggelos K. creators_id: sotirios.tsaftaris@imtlucca.it creators_id: creators_id: title: DNA as a medium for storing digital signals ispublished: pub subjects: QA75 subjects: QH426 divisions: CSA full_text_status: public abstract: Motivated by the storage capacity and efficiency of the DNA molecule in this paper we propose to utilize DNA molecules to store digital signals. We show that hybridization of DNA molecules can be used as a similarity criterion for retrieving digital signals encoded and stored in a DNA database. Since retrieval is achieved through hybridization of query and data carrying DNA molecules, we present a mathematical model to estimate hybridization efficiency (also known as selectivity annealing). We show that selectivity annealing is inversely proportional to the mean squared error (MSE) of the encoded signal values. In addition, we show that the concentration of the molecules plays the same role as the decision threshold employed in digital signal matching algorithms. Finally, similarly to the digital domain, we define a DNA signal-to-noise ratio (SNR) measure to assess the performance of the DNA-based retrieval scheme. Simulations are presented to validate our arguments. date: 2006-08 date_type: published publisher: The MIT Press pagerange: 303-309 event_title: Artificial Life X : Proceedings of the Tenth International Conference on the Simulation and Synthesis of Living Systems refereed: TRUE isbn: 9780262681629 book_title: Artificial life X: proceedings of the tenth international conference on the simulation and synthesis of living systems editors_name: Rocha, Luis Mateus related_url_url: http://ivpl.eecs.northwestern.edu/system/files/ALIFEX_tsaftaris.pdf related_url_type: author citation: Tsaftaris, Sotirios A. and Hatzimanikati, Vassily and Katsaggelos, Aggelos K. DNA as a medium for storing digital signals. In: Artificial life X: proceedings of the tenth international conference on the simulation and synthesis of living systems. The MIT Press , pp. 303-309. ISBN 9780262681629 (2006) document_url: http://eprints.imtlucca.it/812/1/Tsaftaris_2006.pdf