relation: http://eprints.imtlucca.it/845/
title: A new quantitative imaging biomarker for identifying critical coronary artery stenosis with myocardial BOLD MRI
creator: Tsaftaris, Sotirios A.
creator: Zhou, Xiangzhi 
creator: Li, Debiao
creator: Dharmakumar, Rohan
subject: QA76 Computer software
subject: RC Internal medicine
subject: TK Electrical engineering. Electronics Nuclear engineering
description: Blood-oxygen-level dependent (BOLD) MRI may be used for detecting myocardial oxygenation changes secondary to coronary artery stenosis (CAS). Under pharmacological stress, areas of the myocardium supplied by a stenotic coronary artery appear hypointense relative to healthy regions in BOLD images. The purpose of this work is to present a fundamentally new approach for visualizing and quantifying regional myocardial BOLD signal changes. This approach, tested in canines, relies on the statistical identification of myocardial pixels affected by CAS, correlates strongly with true flow measurements, and most importantly, leads to a significant increase in sensitivity to microvascular flow changes compared to previous approaches.
date: 2010
type: Conference or Workshop Item
type: PeerReviewed
identifier:   Tsaftaris, Sotirios A. and Zhou, Xiangzhi  and Li, Debiao and Dharmakumar, Rohan  A new quantitative imaging biomarker for identifying critical coronary artery stenosis with myocardial BOLD MRI.  In: 18th Meeting of the international society for magnetic resonance in medicine, 1-7 May 2010,  Stockholm, Sweden       (Unpublished)   (2010)  
relation: http://www.ismrm.org/10/ep4.htm#CV1