eprintid: 845
rev_number: 16
eprint_status: archive
userid: 35
dir: disk0/00/00/08/45
datestamp: 2011-09-08 12:42:01
lastmod: 2013-03-05 15:39:18
status_changed: 2011-09-08 12:42:01
type: conference_item
metadata_visibility: show
item_issues_count: 0
creators_name: Tsaftaris, Sotirios A.
creators_name: Zhou, Xiangzhi 
creators_name: Li, Debiao
creators_name: Dharmakumar, Rohan
creators_id: sotirios.tsaftaris@imtlucca.it
creators_id: 
creators_id: 
creators_id: 
title: A new quantitative imaging biomarker for identifying critical coronary artery stenosis with myocardial BOLD MRI
ispublished: unpub
subjects: QA76
subjects: RC
subjects: TK
divisions: CSA
full_text_status: none
pres_type: poster
abstract: Blood-oxygen-level dependent (BOLD) MRI may be used for detecting myocardial oxygenation changes secondary to coronary artery stenosis (CAS). Under pharmacological stress, areas of the myocardium supplied by a stenotic coronary artery appear hypointense relative to healthy regions in BOLD images. The purpose of this work is to present a fundamentally new approach for visualizing and quantifying regional myocardial BOLD signal changes. This approach, tested in canines, relies on the statistical identification of myocardial pixels affected by CAS, correlates strongly with true flow measurements, and most importantly, leads to a significant increase in sensitivity to microvascular flow changes compared to previous approaches.
date: 2010
event_title: 18th Meeting of the international society for magnetic resonance in medicine
event_location:  Stockholm, Sweden
event_dates: 1-7 May 2010
event_type: conference
refereed: TRUE
official_url: http://www.ismrm.org/10/ep4.htm#CV1
citation:   Tsaftaris, Sotirios A. and Zhou, Xiangzhi  and Li, Debiao and Dharmakumar, Rohan  A new quantitative imaging biomarker for identifying critical coronary artery stenosis with myocardial BOLD MRI.  In: 18th Meeting of the international society for magnetic resonance in medicine, 1-7 May 2010,  Stockholm, Sweden       (Unpublished)   (2010)