relation: http://eprints.imtlucca.it/846/
title: Dual contrast cellular MRI
creator: Dharmakumar, Rohan
creator: Zhang, Zheng 
creator: Koktzoglou, Ioannis
creator: Tsaftaris, Sotirios A.
creator: Li, Debiao
subject: QA76 Computer software
subject: RC Internal medicine
subject: TK Electrical engineering. Electronics Nuclear engineering
description: Negative contrast MRI methods utilizing local magnetic susceptibility shifting (LMS) agents have become an active area of cellular imaging research. However, visualizing and tracking labeled cells on the basis of negative contrast is often plagued by limited specificity and/or sensitivity. Here we report on a cellular MRI method that generates a new contrast with a distinct topology for identifying labeled cells permitting significant improvement in  sensitivity and specificity. Specifically, we show that FLAPS MRI [1],MRI can be used to generate fast three-dimensional images of tissue that can be rapidly  processed to generate quantitative metrics enabling color overlays indicative of regions containing labeled cells.
date: 2010
type: Conference or Workshop Item
type: PeerReviewed
identifier:   Dharmakumar, Rohan and Zhang, Zheng  and Koktzoglou, Ioannis and Tsaftaris, Sotirios A. and Li, Debiao  Dual contrast cellular MRI.  In: 18th Meeting of the international society for magnetic resonance in medicine, 1-7 May 2010,  Stockholm, Sweden       (Unpublished)   (2010)  
relation: http://eta2.bio.cmu.edu/ISMRM/ISMRM%202010%20Stockholm/files/4188_6096.pdf