IMT Institutional Repository: No conditions. Results ordered -Date Deposited. 2024-03-28T09:36:02ZEPrintshttp://eprints.imtlucca.it/images/logowhite.pnghttp://eprints.imtlucca.it/2016-04-20T09:10:28Z2016-04-20T09:10:28Zhttp://eprints.imtlucca.it/id/eprint/3463This item is in the repository with the URL: http://eprints.imtlucca.it/id/eprint/34632016-04-20T09:10:28ZLigandi endogeni per i recettori delle benzodiazepine: nuovo approccio allo studio della biologia dell’ansiaDonatella MarazzitiPietro Pietrinipietro.pietrini@imtlucca.itClaudia MartiniGino GiannacciniAntonio LucacchiniGian Franco PlacidiGiovanni Battista Cassano2016-03-23T13:36:09Z2016-04-06T07:12:43Zhttp://eprints.imtlucca.it/id/eprint/3324This item is in the repository with the URL: http://eprints.imtlucca.it/id/eprint/33242016-03-23T13:36:09ZBenzodiazepine receptors: Inhibitor of tritiated flunitrazepam in sera of psychiatric patientsPietro Pietrinipietro.pietrini@imtlucca.itDonatella MarazzitiGian Franco PlacidiAntonio Lucacchini2016-03-23T13:33:53Z2016-04-06T07:11:35Zhttp://eprints.imtlucca.it/id/eprint/3323This item is in the repository with the URL: http://eprints.imtlucca.it/id/eprint/33232016-03-23T13:33:53ZA 3h-flunitrazepam binding inhibitor is present in psychiatric patients’seraWe investigated the possible existence of endogenous compounds acting on benzodiazepine central receptors in the serum of patients with panic attacks or depression. Our results show the presence of a substance which inhibits the 3H-fiunitrazepam binding specifically in the samples taken from the patients’ groups, and which is not present in normal controls, in the range of concentrations used. This compound has a molecular weight below 1,000 daltons, is heat-stable, and resistant to proteolytic degradation. The demonstration of this inhibitor opens new perspectives in the study of the biochemistry of anxiety.Donatella MarazzitiPietro Pietrinipietro.pietrini@imtlucca.itClaudia MartiniGino GiannacciniGiulio PerugiGian Franco PlacidiGiovanni Battista CassanoAntonio Lucacchini