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Dual contrast cellular MRI

Dharmakumar, Rohan and Zhang, Zheng and Koktzoglou, Ioannis and Tsaftaris, Sotirios A. and Li, Debiao Dual contrast cellular MRI. In: 18th Meeting of the international society for magnetic resonance in medicine, 1-7 May 2010, Stockholm, Sweden (2010)

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Negative contrast MRI methods utilizing local magnetic susceptibility shifting (LMS) agents have become an active area of cellular imaging research. However, visualizing and tracking labeled cells on the basis of negative contrast is often plagued by limited specificity and/or sensitivity. Here we report on a cellular MRI method that generates a new contrast with a distinct topology for identifying labeled cells permitting significant improvement in sensitivity and specificity. Specifically, we show that FLAPS MRI [1],MRI can be used to generate fast three-dimensional images of tissue that can be rapidly processed to generate quantitative metrics enabling color overlays indicative of regions containing labeled cells.

Item Type: Conference or Workshop Item (Poster)
Subjects: Q Science > QA Mathematics > QA76 Computer software
R Medicine > RC Internal medicine
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Research Area: Computer Science and Applications
Depositing User: Users 35 not found.
Date Deposited: 04 Sep 2012 08:34
Last Modified: 20 Nov 2013 10:24
URI: http://eprints.imtlucca.it/id/eprint/1334

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