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Consciousness and Dementia: How the Brain Loses Its Self

Pietrini, Pietro and Salmon, Eric and Nichelli, Paolo Consciousness and Dementia: How the Brain Loses Its Self. In: The Neurology of Consciousness. Academic Press, 204 - 216. ISBN 978-0-12-374168-4 (2008)

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Consciousness is based on the ability to rapidly integrate information and requires the optimal functioning of neural networks widely distributed between the thalami and the whole cortical mantle. Neurodegenerative processes that occur in dementing disorders, including Alzheimer’s disease, frontotemporal dementia and Lewy Body Disease, lead to a progressive disruption of the brain functional and anatomical connectivity that sustains complex mental activity in the human brain. Not only different dementia syndromes affect the brain in different ways but also patients with the same disease may show distinctive clinical features. By combining clinical, neuropsychological and functional brain imaging studies in selected patients, scientists are gaining new insights on the cerebral bases of conscious mental activity and of the neural events that make awareness of the surrounding world and of ourselves to dissolve.

Item Type: Book Section
Uncontrolled Keywords: Dementia; Alzheimer's disease; Psychiatry; Brain Imaging; Brain connectivity
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Research Area: Computer Science and Applications
Depositing User: Caterina Tangheroni
Date Deposited: 18 Feb 2016 12:23
Last Modified: 18 Feb 2016 12:23
URI: http://eprints.imtlucca.it/id/eprint/3074

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