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Molecularly imprinted polymeric micro- and nano-particles for the targeted delivery of active molecules

Gagliardi, Mariacristina and Mazzolai, Barbara Molecularly imprinted polymeric micro- and nano-particles for the targeted delivery of active molecules. Future Medicinal Chemistry, 7 (2). pp. 123-138. ISSN 1756-8919 (2015)

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Abstract

Molecular imprinting (MI) represents a strategy to introduce a ‘molecular memory’ in a polymeric system obtaining materials with specific recognition properties. MI particles can be used as drug delivery systems providing a targeted release and thus reducing the side effects. The introduction of molecular recognition properties on a polymeric drug carrier represents a challenge in the development of targeted delivery systems to increase their efficiency. This review will summarize the limited number of drug delivery MI particles described in the literature along with an overview of potential solutions for a larger exploitation of MI particles as targeted drug delivery carriers. Molecularly imprinted drug carriers can be considered interesting candidates to significantly improve the efficiency of a controlled drug treatment.

Item Type: Article
Identification Number: https://doi.org/10.4155/fmc.14.140
Subjects: Q Science > QD Chemistry
Research Area: Computer Science and Applications
Depositing User: Caterina Tangheroni
Date Deposited: 21 Mar 2016 09:16
Last Modified: 21 Mar 2016 09:19
URI: http://eprints.imtlucca.it/id/eprint/3245

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