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Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data

Azari, Nina P. and Pettigrew, Karen D. and Pietrini, Pietro and Murphy, Declan G. and Horwitz, Barry Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data. International Journal of Neuroscience, 81 (3-4). pp. 1-20. ISSN 0020-7454 (1995)

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Abstract

Sex differences in brain hemispheric structure and function have been reported, and sex-related differences in hemispheric interregional correlations were reported in a prior analysis of resting PET glucose metabolic (rCMRglc) data. To explore further the effect of sex on patterns of hemispheric brain functional interactions, we applied a multiple regression/discriminant analysis to resting rCMRglc PET data from young normal men and women to test two hypotheses: (1) women have stronger between-hemisphere functional interactions; (2) men have stronger within-hemisphere functional interactions. Two separate discriminant functions based on these hypotheses distinguished men and women: the first reflected rCMRglc interdependencies between hemispheres and correctly classified all women and 94% of the men; the second reflected rCMRglc interdependencies within the left hemisphere and correctly classified 82% of the women and 88% of the men. Because the discriminant functions successfully distinguished men and women, these results provide support for both hypotheses.

Item Type: Article
Identification Number: https://doi.org/10.3109/00207459509015294
Uncontrolled Keywords: Human; Sex; Positron emission tomography; Discriminant analysis; Cerebral metabolism; Brain.
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Research Area: Computer Science and Applications
Depositing User: Caterina Tangheroni
Date Deposited: 04 Apr 2016 08:25
Last Modified: 04 Apr 2016 11:54
URI: http://eprints.imtlucca.it/id/eprint/3342

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