Cristea, Ioana A. and Gentili, Claudio and Pietrini, Pietro and Cuijpers, Pim (Review article) Sponsorship bias in the comparative efficacy of psychotherapy and pharmacotherapy for adult depression: meta-analysis. The British Journal of Psychiatry. ISSN 0007-1250 (2016)
Full text not available from this repository.Abstract
Background:Sponsorship bias has never been investigated for non-pharmacological treatments like psychotherapy.AimsWe examined industry funding and author financial conflict of interest (COI) in randomised controlled trials directly comparing psychotherapy and pharmacotherapy in depression.Method: We conducted a meta-analysis with subgroup comparisons for industry v. non-industry-funded trials, and respectively for trial reports with author financial COI v. those without.Results: In total, 45 studies were included. In most analyses, pharmacotherapy consistently showed significant effectiveness over psychotherapy, g = -0.11 (95% CI -0.21 to -0.02) in industry-funded trials. Differences between industry and non-industry-funded trials were significant, a result only partly confirmed in sensitivity analyses. We identified five instances where authors of the original article had not reported financial COI.ConclusionsIndustry-funded trials for depression appear to subtly favour pharmacotherapy over psychotherapy. Disclosure of all financial ties with the pharmaceutical industry should be encouraged.
| Item Type: | Article |
|---|---|
| Identification Number: | https://doi.org/10.1192/bjp.bp.115.179275 |
| Additional Information: | PMID: 27810891 |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Research Area: | Computer Science and Applications |
| Depositing User: | Caterina Tangheroni |
| Date Deposited: | 28 Nov 2016 17:08 |
| Last Modified: | 28 Nov 2016 17:08 |
| URI: | http://eprints.imtlucca.it/id/eprint/3603 |
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