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Procoagulant control strategies for the human blood clotting process

Laurino, Marco and Menara, Tommaso and Stella, Alessandro and Betta, Monica and Landi, Alberto Procoagulant control strategies for the human blood clotting process. In: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), August 25-29, 2015, Milan, Italy pp. 4439-4442. ISSN 1558-4615. ISBN 978-1-4244-9271-8. (2015)

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This paper describes the comparison between two drug control strategies to hemophilia A. To emulate blood clotting and the pathological condition of hemophilia, a mathematical model composed by 14 ordinary differential equations is considered. We adopt a variable structure non-linear PID approach and a Model Predictive Control in order to control the dosage of procoagulant factor used in the treatment of hemophiliac patient. The two control actions are sampled for a practical application. Finally, we discuss and compare the results of the two control approaches, introducing a suited control index (eINR).

Item Type: Conference or Workshop Item (Paper)
Identification Number: 10.1109/EMBC.2015.7319380
Subjects: Q Science > QH Natural history > QH301 Biology
R Medicine > R Medicine (General)
Research Area: Computer Science and Applications
Depositing User: Caterina Tangheroni
Date Deposited: 04 Sep 2017 13:44
Last Modified: 04 Sep 2017 13:44
URI: http://eprints.imtlucca.it/id/eprint/3771

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