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DNA as a medium for storing digital signals

Tsaftaris, Sotirios A. and Hatzimanikati, Vassily and Katsaggelos, Aggelos K. DNA as a medium for storing digital signals. In: Artificial life X: proceedings of the tenth international conference on the simulation and synthesis of living systems. The MIT Press , pp. 303-309. ISBN 9780262681629 (2006)

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Motivated by the storage capacity and efficiency of the DNA molecule in this paper we propose to utilize DNA molecules to store digital signals. We show that hybridization of DNA molecules can be used as a similarity criterion for retrieving digital signals encoded and stored in a DNA database. Since retrieval is achieved through hybridization of query and data carrying DNA molecules, we present a mathematical model to estimate hybridization efficiency (also known as selectivity annealing). We show that selectivity annealing is inversely proportional to the mean squared error (MSE) of the encoded signal values. In addition, we show that the concentration of the molecules plays the same role as the decision threshold employed in digital signal matching algorithms. Finally, similarly to the digital domain, we define a DNA signal-to-noise ratio (SNR) measure to assess the performance of the DNA-based retrieval scheme. Simulations are presented to validate our arguments.

Item Type: Book Section
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Q Science > QH Natural history > QH426 Genetics
Research Area: Computer Science and Applications
Depositing User: Users 35 not found.
Date Deposited: 12 Aug 2011 09:27
Last Modified: 05 Mar 2013 15:47
URI: http://eprints.imtlucca.it/id/eprint/812

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